The best defence against bedbugs is supposedly that powder that contains silica or glass or something, so when they walk over it, it scratches their body and they die from it. Can't evolve a resistance to being cut open, I guess. The heat necessary to kill bedbugs (50+ degrees C) can't be achieved using interior heating. An episode of Verminators showed how they do it. First they seal and caulk the entire room, then they bring in these gigantic (man-size) space-heaters and crank them up. That show dealt with some unmentionably nasty bedbug infestations. I'm talking hundreds in one apartment.