This whole site is going to look very impressive once finished. Three 500ft+ buildings going up will really add to the already impressive canyon effect happening along the Gardener.
Walking distance to:
Bars
Harbourfront
Jack Layton ferry terminal
Eatons Centre which will house the biggest Nordstrom in North America
Shuttles to Billy Bishop airport
Train to Pearson airport
ACC
CN Tower
Rogers Centre
Ripleys aquarium
TIFF
Work if you work in financial district
TTC which will easily take you to CNE, bmo fields, china town
Taxi everywhere no matter how late
Not sure if that qualifies it as being the best location in NA. I think if you take any good location in NYC, Chicago, etc, you could easily come up with a longer list of nearby attractions.