Let my clarify my earlier comment.
If infill on existing lots <15 ft wide between lot lines then I think the following model has merit.
Ground level, street entrance, foyer, closets, rear entry from single car garage.
2nd level, rear dining, rear deck, center kitchen w/island, front living room,
3rd level, 2 bedrooms/offices at each end, bathroom and laundry central,
4th level, master front with balcony, walk-in closet central, master bath rear.
Probably building footprint of 30 to 36 ft front to back, plus 6ft at front and 16ft at back for the lot.